Resveratrol and Red Wine Polyphenols
These products were developed by Interpharma Praha in collaboration with Biophysica, Inc. of San Diego, California.
Recent scientific references regarding Resveratrol:
BBC News, 2006/11/01
Wine 'allows guilt-free gluttony'. A chemical found in red wine could make guilt-free gluttony a reality, an international study suggests.
When given to mice, it countered some effects of a high-calorie diet, improving their health and increasing their life-span, the team reported. However, the chemical could not reverse all consequences of overeating - the mice did not lose any weight. Writing in the journal Nature, the team said its findings could, in the future, help obese humans.
It could be the breakthrough of the year, with massive possibilities for treating human beings
Steve Bloom, Imperial College
The molecule, called resveratrol, is found in red grapes or wine. Previous research has revealed the substance has anti-ageing effects in some organisms, extending the lifespan of yeast by 60%, worms and flies by 30%, and fish by about 60%. It has also been suggested the reported health benefit of red wine may also be down to the resveratrol.
Resveratrol (as wells as Curcumin, Boswellia and Green tea catechins) was reviewed as natural immunomodulator with an excellent safety profile and a promising potential for treating inflammations, such as IBD (inflammatory bowel disease).
The New York Times (June 4, 2008), by Nicholas Wade
New Hints Seen That Red Wine May Slow Aging
Scientists from the University of Wisconsin conducted a study comparing mice fed resveratrol with mice on a caloric-restricted diet and mice on a normal diet. In the resveratrol fed mice, the same effects on gene expression, associated with heart, brain and skeletal muscle aging, were found as in the caloric-restricted mice. The researchers concluded that resveratrol can mimic many of the effects of a caloric-restricted diet ”at doses that can readily be achieved in humans” and suggested that dietary consumption of relatively low doses of resveratrol partially mimics caloric restriction and inhibits some aspects of the aging process.
Barger JL, Kayo T, Vann JM, Arias EB, Wang J, et al. (2008)
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice.
http://www.ncbi.nlm.nih.gov/Abstract
Clarke JO, Mullin GE.
A review of complementary and alternative approaches to immunomodulation.
http://www.ncbi.nlm.nih.gov/Abstract
de Cabo R, Sinclair DA.
Resveratrol improves health and survival of mice on a high-calorie diet.
http://www.ncbi.nlm.nih.gov/Abstract
Delmas D, Jannin B, Latruffe N.
Resveratrol: preventing properties against vascular alterations and ageing.
http://www.ncbi.nlm.nih.gov/Abstract
Harper CE, Patel BB, Wang J, Arabshahi A, Eltoum IA, Lamartiniere CA.
Resveratrol suppresses prostate cancer progression in transgenic mice.
http://www.ncbi.nlm.nih.gov/Abstract
Michael Mason (NYT) – Science – News, October 31, 2006, New York Times
One for the ages: A prescription that may extend life
Nicholas Wade (NYT) – U.S. – News, November 2, 2006, New York Times
Yes, Red Wine Holds Answer. Check Dosage.
Zachary M. Seward, Wall Street Journal (Eastern edition), New York, N.Y.: Nov 30, 2006. pg. D.1
Quest for Youth Drives Craze for “Wine” Pills; Consumers Flock to Resveratrol, Though Anti-Aging Properties Have Been Shown Only in Mice
M. Emília Juan, M. Pilar Vinardell and Joana M. Planas2
The Daily Oral Administration of High Doses of trans-Resveratrol to Rats for 28 Days Is Not Harmful1
Koo SH, Montminy M.
In vino veritas: a tale of two sirt1s?
Penumathsa SV, Thirunavukkarasu M, Koneru S, Juhasz B, Zhan L, Pant R, Menon VP, Otani H, Maulik N.
Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat.